Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/22/21 12:00 PM | 9/22/21 12:00 PM | FC Nantes | Stade Brest 29 | 3-1 | 2 - 5 points |
| 9/22/21 12:00 PM | 9/22/21 12:00 PM | Stade Rennes | Clermont Foot | 6-0 | 2 - 5 points |
| 9/22/21 12:00 PM | 9/22/21 12:00 PM | OSC Lille | Stade Reims | 2-1 | 2 - 5 points |
| 9/22/21 12:00 PM | 9/22/21 12:00 PM | AS Monaco | AS St. Etienne | 3-1 | 2 - 5 points |
| 9/22/21 12:00 PM | 9/22/21 12:00 PM | HSC Montpellier | Girondins Bordeaux | 3-3 | 2 - 5 points |
| 9/22/21 2:00 PM | 9/22/21 2:00 PM | SCO Angers | Olympique Marseille | 0-0 | 2 - 5 points |
| 9/22/21 2:00 PM | 9/22/21 2:00 PM | RC Lens | Racing Club Strasbourg | 0-1 | 2 - 5 points |
| 9/22/21 2:00 PM | 9/22/21 2:00 PM | FC Lorient | OGC Nice | 1-0 | 2 - 5 points |
| 9/22/21 2:00 PM | 9/22/21 2:00 PM | Olympique Lyon | ES Troyes AC | 3-1 | 2 - 5 points |
| 9/22/21 2:00 PM | 9/22/21 2:00 PM | FC Metz | Paris St. Germain | 1-2 | 2 - 5 points |