Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/10/21 2:00 PM | 9/10/21 2:00 PM | FC Lorient | OSC Lille | 2-1 | 2 - 5 points |
| 9/11/21 10:00 AM | 9/11/21 10:00 AM | Paris St. Germain | Clermont Foot | 4-0 | 2 - 5 points |
| 9/11/21 2:00 PM | 9/11/21 2:00 PM | AS Monaco | Olympique Marseille | 0-2 | 2 - 5 points |
| 9/12/21 6:00 AM | 9/12/21 6:00 AM | HSC Montpellier | AS St. Etienne | 2-0 | 2 - 5 points |
| 9/12/21 8:00 AM | 9/12/21 8:00 AM | Girondins Bordeaux | RC Lens | 2-3 | 2 - 5 points |
| 9/12/21 8:00 AM | 9/12/21 8:00 AM | Stade Brest 29 | SCO Angers | 1-1 | 2 - 5 points |
| 9/12/21 8:00 AM | 9/12/21 8:00 AM | FC Metz | ES Troyes AC | 0-2 | 2 - 5 points |
| 9/12/21 8:00 AM | 9/12/21 8:00 AM | Stade Rennes | Stade Reims | 0-2 | 2 - 5 points |
| 9/12/21 10:05 AM | 9/12/21 10:05 AM | FC Nantes | OGC Nice | 0-2 | 2 - 5 points |
| 9/12/21 1:45 PM | 9/12/21 1:45 PM | Olympique Lyon | Racing Club Strasbourg | 3-1 | 2 - 5 points |