Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/15/21 2:00 PM | 10/15/21 2:00 PM | Paris St. Germain | SCO Angers | 2-1 | 2 - 5 points |
| 10/16/21 10:00 AM | 10/16/21 10:00 AM | Clermont Foot | OSC Lille | 1-0 | 2 - 5 points |
| 10/16/21 2:00 PM | 10/16/21 2:00 PM | Olympique Lyon | AS Monaco | 2-0 | 2 - 5 points |
| 10/17/21 6:00 AM | 10/17/21 6:00 AM | ES Troyes AC | OGC Nice | 1-0 | 2 - 5 points |
| 10/17/21 8:00 AM | 10/17/21 8:00 AM | Racing Club Strasbourg | AS St. Etienne | 5-1 | 2 - 5 points |
| 10/17/21 8:00 AM | 10/17/21 8:00 AM | Girondins Bordeaux | FC Nantes | 1-1 | 2 - 5 points |
| 10/17/21 8:00 AM | 10/17/21 8:00 AM | Stade Brest 29 | Stade Reims | 1-1 | 2 - 5 points |
| 10/17/21 8:00 AM | 10/17/21 8:00 AM | FC Metz | Stade Rennes | 0-3 | 2 - 5 points |
| 10/17/21 10:05 AM | 10/17/21 10:05 AM | HSC Montpellier | RC Lens | 1-0 | 2 - 5 points |
| 10/17/21 1:45 PM | 10/17/21 1:45 PM | Olympique Marseille | FC Lorient | 4-1 | 2 - 5 points |