Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 8/13/21 10:45 AM | 8/13/21 10:45 AM | Pordenone | Spezia Calcio | 1-3 | 5 - 7 points |
| 8/13/21 11:00 AM | 8/13/21 11:00 AM | Genua CFC | AC Perugia | 3-2 | 5 - 7 points |
| 8/13/21 1:45 PM | 8/13/21 1:45 PM | Udinese Calcio | Ascoli Calcio | 3-1 | 5 - 7 points |
| 8/13/21 2:05 PM | 8/13/21 2:05 PM | Fiorentina | Cosenza Calcio | 4-0 | 5 - 7 points |
| 8/14/21 10:45 AM | 8/14/21 10:45 AM | Benevento Calcio | SPAL Ferrara | 2-1a.e.t | 5 - 7 points |
| 8/14/21 11:00 AM | 8/14/21 11:00 AM | AS Cittadella | AC Monza | 2-1 | 5 - 7 points |
| 8/14/21 1:45 PM | 8/14/21 1:45 PM | Hellas Verona | US Catanzaro 1929 | 3-0 | 5 - 7 points |
| 8/14/21 2:00 PM | 8/14/21 2:00 PM | Cagliari Calcio | Pisa Sporting Club | 3-1 | 5 - 7 points |
| 8/15/21 10:45 AM | 8/15/21 10:45 AM | FC Empoli | Vicenza Calcio | 4-2 | 5 - 7 points |
| 8/15/21 11:00 AM | 8/15/21 11:00 AM | Parma Calcio 1913 | US Lecce | 1-3 | 5 - 7 points |
| 8/15/21 1:45 PM | 8/15/21 1:45 PM | FC Venice | Frosinone Calcio | 9-8a.PSO | 5 - 7 points |
| 8/15/21 2:00 PM | 8/15/21 2:00 PM | FC Turin | US Cremonese | 4-1a.PSO | 5 - 7 points |
| 8/16/21 10:45 AM | 8/16/21 10:45 AM | FC Crotone | Brescia Calcio | 6-4a.PSO | 5 - 7 points |
| 8/16/21 11:00 AM | 8/16/21 11:00 AM | FC Bologna | Ternana Calcio | 4-5 | 5 - 7 points |
| 8/16/21 1:45 PM | 8/16/21 1:45 PM | US Salernitana | Reggina 1914 | 2-0 | 5 - 7 points |
| 8/16/21 2:00 PM | 8/16/21 2:00 PM | Sampdoria Genua | Alessandria Calcio | 3-2 | 5 - 7 points |