Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 1/21/22 1:30 PM | 1/21/22 12:30 PM | Eintracht Frankfurt | Arminia Bielefeld | 0-2 | 1 - 3 points |
| 1/22/22 8:30 AM | 1/21/22 12:30 PM | Bor. Mönchengladbach | 1. FC Union Berlin | 1-2 | 1 - 3 points |
| 1/22/22 8:30 AM | 1/21/22 12:30 PM | Bayer 04 Leverkusen | FC Augsburg | 5-1 | 1 - 3 points |
| 1/22/22 8:30 AM | 1/21/22 12:30 PM | 1899 Hoffenheim | Borussia Dortmund | 2-3 | 1 - 3 points |
| 1/22/22 8:30 AM | 1/21/22 12:30 PM | SC Freiburg | VfB Stuttgart | 2-0 | 1 - 3 points |
| 1/22/22 8:30 AM | 1/21/22 12:30 PM | SpVgg Greuther Fürth | FSV Mainz 05 | 2-1 | 1 - 3 points |
| 1/22/22 11:30 AM | 1/21/22 12:30 PM | VfL Bochum | 1. FC Köln | 2-2 | 1 - 3 points |
| 1/23/22 8:30 AM | 1/21/22 12:30 PM | RB Leipzig | VfL Wolfsburg | 2-0 | 1 - 3 points |
| 1/23/22 10:30 AM | 1/21/22 12:30 PM | Hertha BSC | FC Bayern Munich | 1-4 | 1 - 3 points |