Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/3/21 1:30 PM | 12/3/21 12:30 PM | 1. FC Union Berlin | RB Leipzig | 2-1 | 1 - 3 points |
| 12/4/21 8:30 AM | 12/3/21 12:30 PM | FSV Mainz 05 | VfL Wolfsburg | 3-0 | 1 - 3 points |
| 12/4/21 8:30 AM | 12/3/21 12:30 PM | 1899 Hoffenheim | Eintracht Frankfurt | 3-2 | 1 - 3 points |
| 12/4/21 8:30 AM | 12/3/21 12:30 PM | Bayer 04 Leverkusen | SpVgg Greuther Fürth | 7-1 | 1 - 3 points |
| 12/4/21 8:30 AM | 12/3/21 12:30 PM | Arminia Bielefeld | 1. FC Köln | 1-1 | 1 - 3 points |
| 12/4/21 8:30 AM | 12/3/21 12:30 PM | FC Augsburg | VfL Bochum | 2-3 | 1 - 3 points |
| 12/4/21 11:30 AM | 12/3/21 12:30 PM | Borussia Dortmund | FC Bayern Munich | 2-3 | 1 - 3 points |
| 12/5/21 8:30 AM | 12/3/21 12:30 PM | VfB Stuttgart | Hertha BSC | 2-2 | 1 - 3 points |
| 12/5/21 10:30 AM | 12/3/21 12:30 PM | Bor. Mönchengladbach | SC Freiburg | 0-6 | 1 - 3 points |