| Date | Home | Away | Result |
|---|---|---|---|
| 10/7/22 1:30 PM | 1899 Hoffenheim | Werder Bremen | 1-2 |
| 10/8/22 8:30 AM | VfL Bochum | Eintracht Frankfurt | 3-0 |
| 10/8/22 8:30 AM | Bayer 04 Leverkusen | FC Schalke 04 | 4-0 |
| 10/8/22 8:30 AM | FSV Mainz 05 | RB Leipzig | 1-1 |
| 10/8/22 8:30 AM | FC Augsburg | VfL Wolfsburg | 1-1 |
| 10/8/22 11:30 AM | Borussia Dortmund | FC Bayern Munich | 2-2 |
| 10/9/22 8:30 AM | Bor. Mönchengladbach | 1. FC Köln | 5-2 |
| 10/9/22 10:30 AM | Hertha BSC | SC Freiburg | 2-2 |
| 10/9/22 12:30 PM | VfB Stuttgart | 1. FC Union Berlin | 0-1 |