| Date | Home | Away | Result |
|---|---|---|---|
| 9/9/22 1:30 PM | Werder Bremen | FC Augsburg | 0-1 |
| 9/10/22 8:30 AM | Eintracht Frankfurt | VfL Wolfsburg | 0-1 |
| 9/10/22 8:30 AM | RB Leipzig | Borussia Dortmund | 3-0 |
| 9/10/22 8:30 AM | FC Bayern Munich | VfB Stuttgart | 2-2 |
| 9/10/22 8:30 AM | Hertha BSC | Bayer 04 Leverkusen | 2-2 |
| 9/10/22 8:30 AM | 1899 Hoffenheim | FSV Mainz 05 | 4-1 |
| 9/10/22 11:30 AM | FC Schalke 04 | VfL Bochum | 3-1 |
| 9/11/22 8:30 AM | 1. FC Köln | 1. FC Union Berlin | 0-1 |
| 9/11/22 10:30 AM | SC Freiburg | Bor. Mönchengladbach | 0-0 |