| Date | Home | Away | Result |
|---|---|---|---|
| 8/19/22 1:30 PM | Bor. Mönchengladbach | Hertha BSC | 1-0 |
| 8/20/22 8:30 AM | FC Augsburg | FSV Mainz 05 | 1-2 |
| 8/20/22 8:30 AM | Borussia Dortmund | Werder Bremen | 2-3 |
| 8/20/22 8:30 AM | VfL Wolfsburg | FC Schalke 04 | 0-0 |
| 8/20/22 8:30 AM | VfB Stuttgart | SC Freiburg | 0-1 |
| 8/20/22 8:30 AM | Bayer 04 Leverkusen | 1899 Hoffenheim | 0-3 |
| 8/20/22 11:30 AM | 1. FC Union Berlin | RB Leipzig | 2-1 |
| 8/21/22 8:30 AM | Eintracht Frankfurt | 1. FC Köln | 1-1 |
| 8/21/22 10:30 AM | VfL Bochum | FC Bayern Munich | 0-7 |