| Date | Home | Away | Result |
|---|---|---|---|
| 10/28/22 1:30 PM | Werder Bremen | Hertha BSC | 1-0 |
| 10/29/22 8:30 AM | VfB Stuttgart | FC Augsburg | 2-1 |
| 10/29/22 8:30 AM | RB Leipzig | Bayer 04 Leverkusen | 2-0 |
| 10/29/22 8:30 AM | FC Bayern Munich | FSV Mainz 05 | 6-2 |
| 10/29/22 8:30 AM | VfL Wolfsburg | VfL Bochum | 4-0 |
| 10/29/22 11:30 AM | Eintracht Frankfurt | Borussia Dortmund | 1-2 |
| 10/30/22 9:30 AM | 1. FC Union Berlin | Bor. Mönchengladbach | 2-1 |
| 10/30/22 11:30 AM | FC Schalke 04 | SC Freiburg | 0-2 |
| 10/30/22 1:30 PM | 1. FC Köln | 1899 Hoffenheim | 1-1 |