| Date | Home | Away | Result |
|---|---|---|---|
| 11/5/21 2:30 PM | FSV Mainz 05 | Bor. Mönchengladbach | 1-1 |
| 11/6/21 9:30 AM | VfB Stuttgart | Arminia Bielefeld | 0-1 |
| 11/6/21 9:30 AM | VfL Wolfsburg | FC Augsburg | 1-0 |
| 11/6/21 9:30 AM | FC Bayern Munich | SC Freiburg | 2-1 |
| 11/6/21 9:30 AM | VfL Bochum | 1899 Hoffenheim | 2-0 |
| 11/6/21 12:30 PM | RB Leipzig | Borussia Dortmund | 2-1 |
| 11/7/21 8:30 AM | Hertha BSC | Bayer 04 Leverkusen | 1-1 |
| 11/7/21 10:30 AM | 1. FC Köln | 1. FC Union Berlin | 2-2 |
| 11/7/21 12:30 PM | SpVgg Greuther Fürth | Eintracht Frankfurt | 1-2 |