| Date | Home | Away | Result |
|---|---|---|---|
| 9/18/24 6:30 PM | New York City FC | Philadelphia Union | --- |
| 9/18/24 6:30 PM | Toronto FC | Columbus Crew | --- |
| 9/18/24 6:30 PM | New England Revolution | CF Montreal | --- |
| 9/18/24 6:30 PM | Atlanta United FC | Inter Miami CF | --- |
| 9/18/24 7:00 PM | Orlando City | Charlotte FC | --- |
| 9/18/24 7:30 PM | Houston Dynamo | Vancouver Whitecaps | --- |
| 9/18/24 7:30 PM | Nashville SC | Chicago Fire | --- |
| 9/18/24 7:30 PM | Sporting Kansas City | Colorado Rapids | --- |
| 9/18/24 7:30 PM | Minnesota United FC | Cincinnati FC | --- |
| 9/18/24 8:30 PM | Real Salt Lake | FC Dallas | --- |
| 9/18/24 9:30 PM | Los Angeles FC | Austin FC | --- |
| 9/18/24 9:30 PM | Portland Timbers | Los Angeles Galaxy | --- |
| 9/18/24 9:30 PM | Seattle Sounders | San Jose Earthquakes | --- |