| Date | Home | Away | Result |
|---|---|---|---|
| 5/27/23 6:30 PM | Orlando City | Atlanta United FC | 1-1 |
| 5/27/23 6:30 PM | New York City FC | Philadelphia Union | 1-3 |
| 5/27/23 6:30 PM | New England Revolution | Chicago Fire | 3-3 |
| 5/27/23 6:30 PM | Toronto FC | D.C. United | 2-1 |
| 5/27/23 6:30 PM | CF Montreal | Inter Miami CF | 1-0 |
| 5/27/23 7:30 PM | Minnesota United FC | Real Salt Lake | 1-1 |
| 5/27/23 7:30 PM | Houston Dynamo | Austin FC | 2-1 |
| 5/27/23 7:30 PM | St. Louis City SC | Vancouver Whitecaps | 3-1 |
| 5/27/23 8:30 PM | Colorado Rapids | Cincinnati FC | 0-1 |
| 5/27/23 9:30 PM | Los Angeles Galaxy | Charlotte FC | 0-1 |
| 5/27/23 9:30 PM | Seattle Sounders | New York Red Bulls | 1-0 |
| 5/27/23 9:30 PM | San Jose Earthquakes | FC Dallas | 1-1 |
| 5/28/23 2:00 PM | Sporting Kansas City | Portland Timbers | 4-1 |
| 5/28/23 7:30 PM | Nashville SC | Columbus Crew | 3-1 |