| Date | Home | Away | Result |
|---|---|---|---|
| 5/6/23 6:30 PM | San Jose Earthquakes | Los Angeles FC | 2-1 |
| 5/6/23 6:30 PM | Inter Miami CF | Atlanta United FC | 2-1 |
| 5/6/23 6:30 PM | New York Red Bulls | Philadelphia Union | 0-1 |
| 5/6/23 6:30 PM | Charlotte FC | New York City FC | 3-2 |
| 5/6/23 6:30 PM | Cincinnati FC | D.C. United | 2-1 |
| 5/6/23 6:30 PM | Toronto FC | New England Revolution | 0-2 |
| 5/6/23 6:30 PM | CF Montreal | Orlando City | 2-0 |
| 5/6/23 7:30 PM | Houston Dynamo | Real Salt Lake | 0-0 |
| 5/6/23 7:30 PM | Nashville SC | Chicago Fire | 3-0 |
| 5/6/23 9:30 PM | Portland Timbers | Austin FC | 2-2 |
| 5/6/23 9:30 PM | Los Angeles Galaxy | Colorado Rapids | 1-3 |
| 5/6/23 9:30 PM | Vancouver Whitecaps | Minnesota United FC | 3-2 |
| 5/7/23 3:30 PM | Seattle Sounders | Sporting Kansas City | 1-2 |
| 6/7/23 7:35 PM | FC Dallas | St. Louis City SC | 2-0 |